In a mixing bowl, combine ground chicken, garlic powder, onion powder, paprika, salt, and black pepper. Mix until well combined.

Form the mixture into 4 equal patties, about 1/2 inch thick.

Preheat the grill to medium-high heat and lightly oil the grates.

Place the chicken patties on the grill and cook for about 6-7 minutes on each side, or until the internal temperature reaches 165°F (75°C).

If using cheese, add a slice on top of each patty during the last minute of cooking to melt.

Toast the burger buns on the grill until golden brown.

Spread mayonnaise on the bottom half of each bun, add the grilled chicken patty, top with lettuce, tomato, and ketchup, then place the top half of the bun.